PT  - JOURNAL ARTICLE
AU  - G Stoll
AU  - G Schwendemann
AU  - K Heininger
AU  - W Köhne
AU  - H P Hartung
AU  - R Seitz
AU  - K V Toyka
TI  - Relation of clinical, serological, morphological, and electrophysiological findings in galactocerebroside-induced experimental allergic neuritis.
AID  - 10.1136/jnnp.49.3.258
DP  - 1986 Mar 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 258--264
VI  - 49
IP  - 3
4099  - http://jnnp.bmj.com/content/49/3/258.short
4100  - http://jnnp.bmj.com/content/49/3/258.full
SO  - J Neurol Neurosurg Psychiatry1986 Mar 01; 49
AB  - Rabbits were immunised repeatedly with bovine brain galactocerebroside. Almost all animals developed overt polyradiculoneuropathy. Circulating IgG antibodies to galactocerebroside in the serum and deposits of IgG in the spinal roots were detectable weeks before definite clinical, morphological, and electrophysiological alterations occurred. The levels of IgG antibody titres to galactocerebroside did not correlate with the severity of the clinical disease and of nerve conduction slowing. Remyelination and a virtually complete recovery of nerve dysfunction occurred although circulating antibodies to galactocerebroside were still present.