RT Journal Article
SR Electronic
T1 Diffuse cerebrospinal gliomatosis presenting as motor neuron disease for two years.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 275
OP 278
DO 10.1136/jnnp.52.2.275
VO 52
IS 2
A1 M Schmidbauer
A1 C Müller
A1 I Podreka
A1 B Mamoli
A1 E Sluga
A1 L Deecke
YR 1989
UL http://jnnp.bmj.com/content/52/2/275.abstract
AB A patient with symptoms and signs of motor neuron disease for 2 years finally developed sensory disturbances and increased intracranial pressure. MRI and CT showed enlargement of the right side of the cerebellum, the brainstem and parts of the cerebral hemisphere with focal hyperperfusion demonstrated by SPECT. Necropsy revealed a diffuse cerebrospinal gliomatosis with loss of spinal motor neurons in tumour infiltration of the anterior horns. This type of spinal cord involvement is considered responsible for the unusual clinical presentation of the neoplasm.