RT Journal Article
SR Electronic
T1 Neuropsychological deficits in myotonic muscular dystrophy.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 1011
OP 1013
DO 10.1136/jnnp.53.11.1011
VO 53
IS 11
A1 P Malloy
A1 S K Mishra
A1 S H Adler
YR 1990
UL http://jnnp.bmj.com/content/53/11/1011.abstract
AB Twenty patients with myotonic muscular dystrophy (MMD) were compared with twenty controls on a battery of standardised neuropsychiological tests measuring motor and cognitive functions. The MMD patients performed significantly poorer on both motor and cognitive tests, particularly those assessing spatial functions. Although both motor and cognitive scores were correlated with age, significant diagnostic group by age interactions were present only for the motor measures. Therefore, while motor deficits in MMD may progress with ageing, cognitive deficits are mainly developmental and relatively stable.