PT  - JOURNAL ARTICLE
AU  - Graham, E M
AU  - Francis, D A
AU  - Sanders, M D
AU  - Rudge, P
TI  - Ocular inflammatory changes in established multiple sclerosis.
AID  - 10.1136/jnnp.52.12.1360
DP  - 1989 Dec 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 1360--1363
VI  - 52
IP  - 12
4099  - http://jnnp.bmj.com/content/52/12/1360.short
4100  - http://jnnp.bmj.com/content/52/12/1360.full
SO  - J Neurol Neurosurg Psychiatry1989 Dec 01; 52
AB  - Fifty consecutive patients with clinically definite multiple sclerosis were studied to assess the prevalence of concomitant uveitis. Asymptomatic ocular inflammatory changes were found in nine patients (18%) and appeared to show a positive correlation with severe and progressive disease. Conversely uveitis was uncommon in the presence of established optic atrophy which suggests a negative influence on its pathogenesis. In the absence of optic atrophy inflammatory changes in the eye may be a valuable index of disease activity.