RT Journal Article
SR Electronic
T1 Ocular inflammatory changes in established multiple sclerosis.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 1360
OP 1363
DO 10.1136/jnnp.52.12.1360
VO 52
IS 12
A1 E M Graham
A1 D A Francis
A1 M D Sanders
A1 P Rudge
YR 1989
UL http://jnnp.bmj.com/content/52/12/1360.abstract
AB Fifty consecutive patients with clinically definite multiple sclerosis were studied to assess the prevalence of concomitant uveitis. Asymptomatic ocular inflammatory changes were found in nine patients (18%) and appeared to show a positive correlation with severe and progressive disease. Conversely uveitis was uncommon in the presence of established optic atrophy which suggests a negative influence on its pathogenesis. In the absence of optic atrophy inflammatory changes in the eye may be a valuable index of disease activity.