TY - JOUR T1 - Ocular inflammatory changes in established multiple sclerosis. JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 1360 LP - 1363 DO - 10.1136/jnnp.52.12.1360 VL - 52 IS - 12 AU - E M Graham AU - D A Francis AU - M D Sanders AU - P Rudge Y1 - 1989/12/01 UR - http://jnnp.bmj.com/content/52/12/1360.abstract N2 - Fifty consecutive patients with clinically definite multiple sclerosis were studied to assess the prevalence of concomitant uveitis. Asymptomatic ocular inflammatory changes were found in nine patients (18%) and appeared to show a positive correlation with severe and progressive disease. Conversely uveitis was uncommon in the presence of established optic atrophy which suggests a negative influence on its pathogenesis. In the absence of optic atrophy inflammatory changes in the eye may be a valuable index of disease activity. ER -