PT - JOURNAL ARTICLE AU - C Chiron AU - C Raynaud AU - N Tzourio AU - C Diebler AU - O Dulac AU - M Zilbovicius AU - A Syrota TI - Regional cerebral blood flow by SPECT imaging in Sturge-Weber disease: an aid for diagnosis. AID - 10.1136/jnnp.52.12.1402 DP - 1989 Dec 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 1402--1409 VI - 52 IP - 12 4099 - http://jnnp.bmj.com/content/52/12/1402.short 4100 - http://jnnp.bmj.com/content/52/12/1402.full SO - J Neurol Neurosurg Psychiatry1989 Dec 01; 52 AB - Regional cerebral blood flow (rCBF) was studied using SPECT (single photon emission computed tomography) with 133-Xenon in 13 patients with confirmed Sturge-Weber disease, aged 9 months to 18 years. CT scan, performed at the same time, showed evident cerebral angioma in 10 but not in three. A marked hypoperfused area was found in all patients, ranging from -32% to -72% and of the same location as the CT signs. The hypoperfusion seems to result from post ictal phenomenon as well as from chronic ischaemia. SPECT imaging is therefore a sensitive method for visualising intracranial angioma in Sturge-Weber disease and it provides an aid for diagnosis when a CT scan is not reliable.