RT Journal Article
SR Electronic
T1 Regional cerebral blood flow by SPECT imaging in Sturge-Weber disease: an aid for diagnosis.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 1402
OP 1409
DO 10.1136/jnnp.52.12.1402
VO 52
IS 12
A1 Chiron, C
A1 Raynaud, C
A1 Tzourio, N
A1 Diebler, C
A1 Dulac, O
A1 Zilbovicius, M
A1 Syrota, A
YR 1989
UL http://jnnp.bmj.com/content/52/12/1402.abstract
AB Regional cerebral blood flow (rCBF) was studied using SPECT (single photon emission computed tomography) with 133-Xenon in 13 patients with confirmed Sturge-Weber disease, aged 9 months to 18 years. CT scan, performed at the same time, showed evident cerebral angioma in 10 but not in three. A marked hypoperfused area was found in all patients, ranging from -32% to -72% and of the same location as the CT signs. The hypoperfusion seems to result from post ictal phenomenon as well as from chronic ischaemia. SPECT imaging is therefore a sensitive method for visualising intracranial angioma in Sturge-Weber disease and it provides an aid for diagnosis when a CT scan is not reliable.