RT Journal Article
SR Electronic
T1 Results of stereotactic radiosurgery of arteriovenous malformations: an analysis of 52 cases.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 554
OP 558
DO 10.1136/jnnp.52.5.554
VO 52
IS 5
A1 A A Kemeny
A1 P S Dias
A1 D M Forster
YR 1989
UL http://jnnp.bmj.com/content/52/5/554.abstract
AB The stereotactic radiosurgery unit in Sheffield became operational in September 1985 and over 180 patients harbouring AVMs have been treated. The first 52 patients underwent one year follow up angiography and comprise the material for this study. At one year 26 patients (50%) already had a favourable outcome (16 complete and 10 almost complete obliteration). The results were the same in the two sexes. There was a better response in younger patients: under 20 years 75% favourable, between 20 and 40 years 45% favourable and above 40 years about 25% favourable. Malformations in a lateral position appeared to respond better than those in the midline. Lesions fed by vessels from more than one large vessel territory had less chance of complete obliteration at one year than those gaining blood from only one main supply. There was no difference in outcome between small malformations (less than 2 cm3) medium (2-3 cm3) or large (greater than 3 cm3). No immediate morbidity or late side effects were encountered in these patients. Stereotactic radiosurgery is a safe and effective method in the treatment of arteriovenous malformations but there is a relatively long latency. The number of malformations obliterated is expected to be much higher when two years have elapsed after treatment.