RT Journal Article
SR Electronic
T1 Magnetic resonance imaging of the brain and spinal cord in cerebrotendinous xanthomatosis.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 166
OP 167
DO 10.1136/jnnp.53.2.166
VO 53
IS 2
A1 Bencze, K S
A1 Vande Polder, D R
A1 Prockop, L D
YR 1990
UL http://jnnp.bmj.com/content/53/2/166.abstract
AB This reports a 40 year old man with cerebrotendinous xanthomatosis who had bilateral cataracts, enlarged Achilles tendons, progressive dementia, gait disturbance and peripheral neuropathy. Electroencephalography, electromyography, and magnetic resonance imaging (MRI) of the brain and spine were performed. Magnetic resonance imaging revealed cerebral, cerebellar and cervical cord atrophy and white matter involvement in the cerebrum and cerebellum correlating well with the clinical findings. To date there has been one previous report of MRI of the brain in cerebrotendinous xanthomatosis and none of the spinal cord.