TY - JOUR T1 - A fulminant case of Guillain-Barré syndrome: topographic and fibre size related analysis of demyelinating changes. JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 857 LP - 864 DO - 10.1136/jnnp.52.7.857 VL - 52 IS - 7 AU - T Kanda AU - H Hayashi AU - H Tanabe AU - T Tsubaki AU - M Oda Y1 - 1989/07/01 UR - http://jnnp.bmj.com/content/52/7/857.abstract N2 - In a necropsy case of early fulminant Guillain-Barré syndrome, demyelinating changes were observed throughout the peripheral nervous system, most conspicuous in the spinal nerve roots. The central/peripheral nervous system transition regions and most proximal zones of the roots escaped damage. In some root areas there were widespread early changes in myelin sheaths in the absence of significant infiltrates of inflammatory cells. In the fibre size analytical study, small myelinated fibres were preferentially involved. ER -