TY - JOUR T1 - HLA antigens in multiple sclerosis of northern Spanish population. JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 434 LP - 435 DO - 10.1136/jnnp.53.5.434 VL - 53 IS - 5 AU - C López-Larrea AU - D F Uría AU - E Coto Y1 - 1990/05/01 UR - http://jnnp.bmj.com/content/53/5/434.abstract N2 - HLA-A, -B, -C, -DR, -DQ antigens were studied in 43 multiple sclerosis (MS) patients with clinically definite remittent sclerosis from Asturias (North Spain). The prevalence of HLA-B7, B7 and B27 were significantly increased in MS. HLA-B35 was under-represented in these patients. DR2 was increased but not significantly. No association with DQw1 was discovered. The existence of several susceptibility factors in the more common B7/DR2/DQw1 haplotype is discussed. ER -