PT  - JOURNAL ARTICLE
AU  - López-Larrea, C
AU  - Uría, D F
AU  - Coto, E
TI  - HLA antigens in multiple sclerosis of northern Spanish population.
AID  - 10.1136/jnnp.53.5.434
DP  - 1990 May 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 434--435
VI  - 53
IP  - 5
4099  - http://jnnp.bmj.com/content/53/5/434.short
4100  - http://jnnp.bmj.com/content/53/5/434.full
SO  - J Neurol Neurosurg Psychiatry1990 May 01; 53
AB  - HLA-A, -B, -C, -DR, -DQ antigens were studied in 43 multiple sclerosis (MS) patients with clinically definite remittent sclerosis from Asturias (North Spain). The prevalence of HLA-B7, B7 and B27 were significantly increased in MS. HLA-B35 was under-represented in these patients. DR2 was increased but not significantly. No association with DQw1 was discovered. The existence of several susceptibility factors in the more common B7/DR2/DQw1 haplotype is discussed.