RT Journal Article
SR Electronic
T1 HLA antigens in multiple sclerosis of northern Spanish population.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 434
OP 435
DO 10.1136/jnnp.53.5.434
VO 53
IS 5
A1 López-Larrea, C
A1 Uría, D F
A1 Coto, E
YR 1990
UL http://jnnp.bmj.com/content/53/5/434.abstract
AB HLA-A, -B, -C, -DR, -DQ antigens were studied in 43 multiple sclerosis (MS) patients with clinically definite remittent sclerosis from Asturias (North Spain). The prevalence of HLA-B7, B7 and B27 were significantly increased in MS. HLA-B35 was under-represented in these patients. DR2 was increased but not significantly. No association with DQw1 was discovered. The existence of several susceptibility factors in the more common B7/DR2/DQw1 haplotype is discussed.