PT - JOURNAL ARTICLE AU - Rugg, M D AU - Pickles, C D AU - Potter, D D AU - Roberts, R C TI - Normal P300 following extensive damage to the left medial temporal lobe. AID - 10.1136/jnnp.54.3.217 DP - 1991 Mar 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 217--222 VI - 54 IP - 3 4099 - http://jnnp.bmj.com/content/54/3/217.short 4100 - http://jnnp.bmj.com/content/54/3/217.full SO - J Neurol Neurosurg Psychiatry1991 Mar 01; 54 AB - Event-related potentials (ERPs) were recorded during auditory and visual "oddball" tasks from a patient with a severe verbal memory deficit due to a low grade infiltrating glioma which involved the full extent of the left medial temporal lobe. In both sensory modalities, the patient's oddball-evoked P300s were symmetrical and of normal amplitude. These findings are difficult to reconcile with the hypothesis that the hippocampus, or any other medial temporal structure, makes a substantial contribution to the scalp P300.