RT Journal Article
SR Electronic
T1 Normal P300 following extensive damage to the left medial temporal lobe.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 217
OP 222
DO 10.1136/jnnp.54.3.217
VO 54
IS 3
A1 Rugg, M D
A1 Pickles, C D
A1 Potter, D D
A1 Roberts, R C
YR 1991
UL http://jnnp.bmj.com/content/54/3/217.abstract
AB Event-related potentials (ERPs) were recorded during auditory and visual "oddball" tasks from a patient with a severe verbal memory deficit due to a low grade infiltrating glioma which involved the full extent of the left medial temporal lobe. In both sensory modalities, the patient's oddball-evoked P300s were symmetrical and of normal amplitude. These findings are difficult to reconcile with the hypothesis that the hippocampus, or any other medial temporal structure, makes a substantial contribution to the scalp P300.