PT  - JOURNAL ARTICLE
AU  - T Petterson
AU  - I A MacFarlane
AU  - J M MacKenzie
AU  - M D Shaw
TI  - Prolactin secreting pituitary carcinoma.
AID  - 10.1136/jnnp.55.12.1205
DP  - 1992 Dec 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 1205--1206
VI  - 55
IP  - 12
4099  - http://jnnp.bmj.com/content/55/12/1205.short
4100  - http://jnnp.bmj.com/content/55/12/1205.full
SO  - J Neurol Neurosurg Psychiatry1992 Dec 01; 55
AB  - A man with a prolactin secreting pituitary carcinoma was treated by surgery and radiotherapy. Persistent hyperprolactinaemia partially responded to oral bromocriptine for four years. Serum prolactin then rose considerably with rapid, invasive tumour recurrence. Cytotoxic chemotherapy halted tumour progression for twelve months before fatal spread throughout the brain. Failure to normalise serum prolactin with bromocriptine may precede an aggressive course in patients with prolactinoma.