PT  - JOURNAL ARTICLE
AU  - E van Ingelghem
AU  - M van Zandijcke
AU  - M Lammens
TI  - Pure autonomic failure: a new case with clinical, biochemical, and necropsy data.
AID  - 10.1136/jnnp.57.6.745
DP  - 1994 Jun 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 745--747
VI  - 57
IP  - 6
4099  - http://jnnp.bmj.com/content/57/6/745.short
4100  - http://jnnp.bmj.com/content/57/6/745.full
SO  - J Neurol Neurosurg Psychiatry1994 Jun 01; 57
AB  - Postmortem examination of a patient with pure autonomic failure showed loss of intermediolateral column cells and of sympathetic ganglionic neurons; there were Lewy bodies in sympathetic neurons. No neuronal loss or Lewy bodies were seen in pigmented brainstem nuclei. This case indicates that pure autonomic failure can occur in the absence of presymptomatic Parkinson's disease. Furthermore, it supports the view that in pure autonomic failure the lesion is more distal than in autonomic failure associated with multiple system atrophy.