PT - JOURNAL ARTICLE AU - L Cartier AU - J L Castillo AU - J G Cea AU - R Villagra TI - Chronic dacryosialadenitis in HTLV I associated myelopathy. AID - 10.1136/jnnp.58.2.244 DP - 1995 Feb 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 244--246 VI - 58 IP - 2 4099 - http://jnnp.bmj.com/content/58/2/244.short 4100 - http://jnnp.bmj.com/content/58/2/244.full SO - J Neurol Neurosurg Psychiatry1995 Feb 01; 58 AB - A prospective study was carried out on 48 patients with HTLV I associated myelopathy/tropical spastic paraparesis (HAM/TSP) to assess the association between this entity and Sjögren's syndrome. Fourteen patients (29.1%) had chronic dacryosialadenitis confirmed by a positive Schirmer's test and salivary gland biopsy. None of these patients had evidence of collagen disease and tests for Ro, La, and rheumatoid factor were negative except in one case. Therefore, the dacryosialadenitis could not be classified as either primary or secondary Sjögren's syndrome. Ten of the 14 patients (71.4%) had other systems (haematological, articular, dermatological, or respiratory) involved apart from the neurological and exocrine gland pathology. The findings suggest that the dacryosialadenitis associated with HTLV I is a disease of viral origin distinct from Sjögren's syndrome.