TY - JOUR T1 - Benign form of multiple sclerosis: MRI evidence for less frequent and less inflammatory disease activity. JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 1070 LP - 1072 DO - 10.1136/jnnp.57.9.1070 VL - 57 IS - 9 AU - D Kidd AU - A J Thompson AU - B E Kendall AU - D H Miller AU - W I McDonald Y1 - 1994/09/01 UR - http://jnnp.bmj.com/content/57/9/1070.abstract N2 - Data from two serial studies comparing the MRI activity of two groups of 11 patients, one with early relapsing-remitting (mean disease duration 3.5 years), the other benign (mean disease duration 22 years) multiple sclerosis are presented. Those with benign disease developed fewer new or enlarging lesions, and such lesions that occurred had a lower incidence of gadolinium enhancement, a marker of inflammation. These results, when considered in conjunction with other published studies, suggest that both the frequency of new lesions and the amount of inflammation within them influence the development of disability in multiple sclerosis. ER -