PT - JOURNAL ARTICLE AU - A Kinoshita AU - M Hayashi AU - K Miyamoto AU - M Oda AU - H Tanabe TI - Inflammatory demyelinating polyradiculitis in a patient with acute disseminated encephalomyelitis (ADEM). AID - 10.1136/jnnp.60.1.87 DP - 1996 Jan 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 87--90 VI - 60 IP - 1 4099 - http://jnnp.bmj.com/content/60/1/87.short 4100 - http://jnnp.bmj.com/content/60/1/87.full SO - J Neurol Neurosurg Psychiatry1996 Jan 01; 60 AB - A patient with severe acute disseminated encephalomyelitis died 12 days after the first symptom. Necropsy showed widespread severe demyelination in the CNS and some foci of demyelination in the spinal roots. The lesions in the peripheral nervous system were characterised by myelin stripping and the presence of macrophages, being severest in the spinal nerve roots. Some axons were completely demyelinated, whereas the axons themselves were preserved. Pathologically established ongoing demyelination in both CNS and peripheral nervous systems raises the possibility of a shared pathological epitope.