PT  - JOURNAL ARTICLE
AU  - R P Bruyn
AU  - J H Koelman
AU  - D Troost
AU  - J M de Jong
TI  - Motor neuron disease (amyotrophic lateral sclerosis) arising from longstanding primary lateral sclerosis.
AID  - 10.1136/jnnp.58.6.742
DP  - 1995 Jun 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 742--744
VI  - 58
IP  - 6
4099  - http://jnnp.bmj.com/content/58/6/742.short
4100  - http://jnnp.bmj.com/content/58/6/742.full
SO  - J Neurol Neurosurg Psychiatry1995 Jun 01; 58
AB  - Three men were initially diagnosed as having primary lateral sclerosis (PLS), but eventually developed amyotrophic lateral sclerosis (ALS) after 7.5, 9, and at least 27 years. Non-familial ALS and PLS might be different manifestations of a single disease or constitute completely distinct entities. The clinical diagnosis of PLS predicts a median survival that is four to five times longer than in ALS.