RT Journal Article
SR Electronic
T1 Slowly progressive apraxia in Alzheimer's disease.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 312
OP 315
DO 10.1136/jnnp.59.3.312
VO 59
IS 3
A1 R C Green
A1 F C Goldstein
A1 S S Mirra
A1 N P Alazraki
A1 J L Baxt
A1 R A Bakay
YR 1995
UL http://jnnp.bmj.com/content/59/3/312.abstract
AB Slowly progressive apraxia due to Alzheimer's disease was encountered in a 66 year old, right handed man whose initial impairments included coordinated movements of the left hand and some features of the alien hand syndrome. Over four years, the patient developed progressively worsening deficits of memory and language. A biopsy of his right temporal lobe showed numerous plaques and neurofibrillary tangles. Pronounced right parietal lobe hypoperfusion on serial SPECT suggests involvement of this region in contralateral praxis.