TY - JOUR T1 - Slowly progressive apraxia in Alzheimer's disease. JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 312 LP - 315 DO - 10.1136/jnnp.59.3.312 VL - 59 IS - 3 AU - R C Green AU - F C Goldstein AU - S S Mirra AU - N P Alazraki AU - J L Baxt AU - R A Bakay Y1 - 1995/09/01 UR - http://jnnp.bmj.com/content/59/3/312.abstract N2 - Slowly progressive apraxia due to Alzheimer's disease was encountered in a 66 year old, right handed man whose initial impairments included coordinated movements of the left hand and some features of the alien hand syndrome. Over four years, the patient developed progressively worsening deficits of memory and language. A biopsy of his right temporal lobe showed numerous plaques and neurofibrillary tangles. Pronounced right parietal lobe hypoperfusion on serial SPECT suggests involvement of this region in contralateral praxis. ER -