RT Journal Article
SR Electronic
T1 A neurological complication of inferior petrosal sinus sampling during investigation for Cushing's disease: a case report.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 527
OP 528
DO 10.1136/jnnp.62.5.527
VO 62
IS 5
A1 Sturrock, N D
A1 Jeffcoate, W J
YR 1997
UL http://jnnp.bmj.com/content/62/5/527.abstract
AB A 45 year old woman with hirsutism was found to have classic biochemical features of ACTH dependent Cushing's disease, with partial cortisol suppression in response to dexamethasone. As no pituitary adenoma could be visualised by CT or MRI, she proceeded to bilateral simultaneous inferior petrosal sinus sampling before possible surgery. During the course of this procedure she had a stroke affecting the brainstem at the level of the pontocerebellar junction. This complication of petrosal sinus sampling has been previously described but is not widely recognised; the procedure should only be undertaken when results of less invasive tests are equivocal.