PT  - JOURNAL ARTICLE
AU  - C P O'Leary
AU  - J Veitch
AU  - W F Durward
AU  - A M Thomas
AU  - J H Rees
AU  - H J Willison
TI  - Acute oropharyngeal palsy is associated with antibodies to GQ1b and GT1a gangliosides.
AID  - 10.1136/jnnp.61.6.649
DP  - 1996 Dec 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 649--651
VI  - 61
IP  - 6
4099  - http://jnnp.bmj.com/content/61/6/649.short
4100  - http://jnnp.bmj.com/content/61/6/649.full
SO  - J Neurol Neurosurg Psychiatry1996 Dec 01; 61
AB  - Three patients with acute oropharyngeal palsy had high titre anti-GQ1b and anti-GT1a IgG antibodies. No patients had ophthalmoplegia or ptosis. In all patients limb ataxia or areflexia were present without notable limb weakness. These patients describe an oropharyngeal variant of Guillain-Barré syndrome in terms of anti-GQ1b antibody reactivity and show that high titre anti-GQ1b antibodies, serologically indistinguishable from those found in Miller Fisher syndrome, can occur in a clinical setting without ophthalmoplegia. The anti-GQ1b and anti-GT1a antibody assays may be helpful tests when considering the differential diagnosis of acute oropharyngeal palsy.