RT Journal Article
SR Electronic
T1 Involuntary movements during thermolesion predict a better outcome after microelectrode guided posteroventral pallidotomy
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 210
OP 213
DO 10.1136/jnnp.63.2.210
VO 63
IS 2
A1 Marcelo Merello
A1 Angel Cammarota
A1 Osvaldo Betti
A1 Maria Ines Nouzeilles
A1 Daniel Cerquetti
A1 Horacio Garcia
A1 Ralph Pikielny
A1 Ramón Leiguarda
YR 1997
UL http://jnnp.bmj.com/content/63/2/210.abstract
AB Eight of the first 15 patients with advanced Parkinson’s disease who underwent microelectrode guided posteroventral pallidotomy developed transient abnormal involuntary movements during thermolesion, four of whom also did so during high frequency macrostimulation. Abnormal involuntary movements found before thermolesion were choreic, ballistic, or choreoathetoid in nature, usually persisted less than 60 minutes, and were contralateral to the site of thermolesion in six and bilateral in two of them. The appearance of abnormal involuntary movements during macrostimulation or thermolesion of the internal globus pallidus correlated with better surgical outcome as measured by UPDRS motor items and CAPIT timed test, so that they seem to be of prognostic value.