TY - JOUR T1 - <strong>Binswanger’s “encephalitis subcorticalis chronica progressiva”</strong> JF - Journal of Neurology, Neurosurgery &amp; Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 308 LP - 308 DO - 10.1136/jnnp.63.3.308 VL - 63 IS - 3 AU - J M S PEARCE Y1 - 1997/09/01 UR - http://jnnp.bmj.com/content/63/3/308.abstract N2 - Otto Binswanger (1852-1929), Professor of Psychiatry in Jena, in 1894 described eight patients with a progressive dementia punctuated by apoplectiform focal attacks whose brains showed diffuse or patchy but selective white matter atrophy, most marked in the temporo-occipital regions with ventricular dilatation. He called it“encephalitis subcorticalis chronica progressiva”. His original description is often misquoted but Förstl’s translation now makes Binswanger’s work accessible1: CLINICAL CRITERIA (p 1184) “The disease begins at the onset of senility (early in the fifties) or in advanced old age (early in the sixties); “slow impairment of intellectual capabilities manifesting primarily by … ER -