RT Journal Article SR Electronic T1 Involvement of the human cerebellum during habituation of the acoustic startle response: A PET study JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP 771 OP 773 DO 10.1136/jnnp.65.5.771 VO 65 IS 5 A1 Dagmar Timmann A1 Christina Musso A1 Florian P Kolb A1 Michel Rijntjes A1 Markus Jüptner A1 Stefan P Müller A1 Hans Christoph Diener A1 Cornelius Weiller YR 1998 UL http://jnnp.bmj.com/content/65/5/771.abstract AB The present study investigated the involvement of the human cerebellum in the habituation of the acoustic startle response using PET. The startle response was elicited in seven young, healthy subjects by a tone presented via headphones. Startle responses were recorded from the right sternocleidomastoid muscle. Regional cerebral blood flow (rCBF) was assessed in nine scans and one startle stimulus was applied during each scan. The reduction of size of the sternocleidomastoid muscle response was correlated with changes in rCBF during the ongoing process of startle response habituation. A significant decrease of rCBF was found in the medial cerebellum. These data are consistent with an involvement of the medial parts of the human cerebellum in non-associative learning as proposed by previous animal studies.