PT - JOURNAL ARTICLE AU - Maria Mataró AU - Maria Antonia Poca AU - Juan Sahuquillo AU - Ampar Cuxart AU - Jordi Iborra AU - María Dolores de la Calzada AU - Carme Junqué TI - Cognitive changes after cerebrospinal fluid shunting in young adults with spina bifida and assumed arrested hydrocephalus AID - 10.1136/jnnp.68.5.615 DP - 2000 May 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 615--621 VI - 68 IP - 5 4099 - http://jnnp.bmj.com/content/68/5/615.short 4100 - http://jnnp.bmj.com/content/68/5/615.full SO - J Neurol Neurosurg Psychiatry2000 May 01; 68 AB - OBJECTIVES To establish whether surgery can improve the neuropsychological functioning of young adult patients with spina bifida and apparent clinically arrested hydrocephalus showing abnormal intracranial pressure. METHODS Twenty three young adults with spina bifida and assumed arrested hydrocephalus (diagnosed as active or compensated by continuous intracranial pressure monitoring) underwent surgery. All patients received neuropsychological examination before surgery and 6 months later. Neuropsychological assessment included tests of verbal and visual memory, visuospatial functions, speed of mental processing, and frontal lobe functions. RESULTS Shunt placement in this subgroup of patients improves neuropsychological functioning, especially in verbal and visual memory and attention and cognitive flexibility. CONCLUSIONS Young adults with spina bifida and suspected non-functioning shunt or non-shunted ventriculomegaly should be carefully monitored to identify those who could benefit from shunting.