TY - JOUR T1 - Early detection of non-compliance in Wilson's disease by consecutive copper determination in cerebrospinal fluid JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 701 LP - 702 DO - 10.1136/jnnp.69.5.701 VL - 69 IS - 5 AU - HANS JOERG STUERENBURG AU - CHRISTIAN EGGERS Y1 - 2000/11/01 UR - http://jnnp.bmj.com/content/69/5/701.abstract N2 - A 41 year old technical employee was diagnosed with Wilson's disease in 1982, 2 years after onset of dysarthria, diplopia, visual deficits, ataxia, and concentration deficits. The patient improved rapidly with d-penicillamine and a copper free diet, and has since returned to normal neurological function. Penicillamine was stopped in 1989 and he changed his diet from copper free to a normal diet in 1987. In 1990 he was put on 800 mg zinc a day. During the past 17 years he underwent 20 determinations of copper concentration in CSF for … ER -