RT Journal Article SR Electronic T1 Limbic encephalitis and antibodies to Ma2: a paraneoplastic presentation of breast cancer JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP 266 OP 268 DO 10.1136/jnnp.69.2.266 VO 69 IS 2 A1 Ian Sutton A1 John Winer A1 David Rowlands A1 Josep Dalmau YR 2000 UL http://jnnp.bmj.com/content/69/2/266.abstract AB A patient with atypical medullary breast cancer is described who presented with symptoms of limbic encephalitis. The patient's serum and CSF contained antibodies that reacted with the nervous system and the tumour. These antibodies recognised Ma2, a neuronal protein related to paraneoplastic limbic and brainstem encephalitis in men with testicular tumours. This report highlights the importance of testing for paraneoplastic antineuronal antibodies in cases of unexplained limbic encephalitis and suggests screening for breast cancer in women with antibodies predominantly directed to Ma2.