RT Journal Article
SR Electronic
T1 Presenile dementia syndromes: an update on taxonomy and diagnosis
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 691
OP 700
DO 10.1136/jnnp.72.6.691
VO 72
IS 6
A1 M D Greicius
A1 M D Geschwind
A1 B L Miller
YR 2002
UL http://jnnp.bmj.com/content/72/6/691.abstract
AB The four major degenerative dementias that often begin in presenescence: are reviewed. These are Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, and Creutzfeldt–Jakob disease. Their epidemiological, genetic, and clinical features are reviewed, and controversies in taxonomy arising from recent discoveries described. Particular attention is given to the pathological role of protein aggregation, which appears to be a factor in each disease.