PT  - JOURNAL ARTICLE
AU  - M Hirayama
AU  - H Fukatsu
AU  - H Watanabe
AU  - Y Koike
AU  - A Noda
AU  - H Ito
AU  - R Kobayashi
AU  - G Sobue
TI  - Sequential constriction of upper airway and vocal cords in sleep apnoea of multiple system atrophy: low field magnetic resonance fluoroscopic study
AID  - 10.1136/jnnp.74.5.642
DP  - 2003 May 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 642--645
VI  - 74
IP  - 5
4099  - http://jnnp.bmj.com/content/74/5/642.short
4100  - http://jnnp.bmj.com/content/74/5/642.full
SO  - J Neurol Neurosurg Psychiatry2003 May 01; 74
AB  - Low field magnetic resonance fluoroscopy was used to clarify temporal and spatial features of airway obstruction in sleep apnoea syndrome (SAS) in multiple system atrophy (MSA), as well as in obstructive SAS (OSAS). 20 patients with OSAS with severe obesity (mean (SD) age 66 (10) years; 16 men, 4 women) and 6 patients with SAS related to probable MSA (60 (9) years; 4 men, 2 women) were studied. In the OSAS group, body mass index, apnoea index, and desaturation index were significantly higher than in the MSA group. In OSAS, simultaneous obstruction extended from the retropalatal pharynx to the retroglossal during sleep on low field magnetic resonance fluoroscopy. In MSA, obstruction of upper airway followed a similar distribution, but obstruction of vocal cords followed upper airway obstruction. In contrast to OSAS, sequentially acting neural mechanisms are suspected in SAS with MSA.