TY - JOUR T1 - Mood changes with deep brain stimulation of STN and GPi: results of a pilot study JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 1584 LP - 1586 DO - 10.1136/jnnp.74.11.1584 VL - 74 IS - 11 AU - M S Okun AU - J Green AU - R Saben AU - R Gross AU - K D Foote AU - J L Vitek Y1 - 2003/11/01 UR - http://jnnp.bmj.com/content/74/11/1584.abstract N2 - The results of this study suggest that there are mood changes associated with deep brain stimulation of the subthalamic nucleus (STN) and the globus pallidus interna (GPi). Further, optimal placement of electrodes in both STN and GPi seems to result in overall improvement in mood and is associated with a lower incidence of adverse mood effects than stimulation outside the optimal site. Preliminary data from this study, however, suggest that slight movement dorsal or ventral to the site of optimal motor performance may be associated with more adverse changes in mood with STN stimulation than with GPi stimulation. ER -