PT  - JOURNAL ARTICLE
AU  - R W Hunt
AU  - S K Warfield
AU  - H Wang
AU  - M Kean
AU  - J J Volpe
AU  - T E Inder
TI  - Assessment of the impact of the removal of cerebrospinal fluid on cerebral tissue volumes by advanced volumetric 3D-MRI in posthaemorrhagic hydrocephalus in a premature infant
AID  - 10.1136/jnnp.74.5.658
DP  - 2003 May 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 658--660
VI  - 74
IP  - 5
4099  - http://jnnp.bmj.com/content/74/5/658.short
4100  - http://jnnp.bmj.com/content/74/5/658.full
SO  - J Neurol Neurosurg Psychiatry2003 May 01; 74
AB  - Current clinical practice in the premature infant with posthaemorrhagic ventricular dilatation (PHVD) includes drainage of cerebrospinal fluid (CSF). This case study used advanced volumetric three dimensional magnetic resonance imaging to document the impact of CSF removal on the volume of regional brain tissues in a premature infant with PHVD. The removal of a large volume of CSF was associated with an identical reduction in CSF volume, but more dramatically with a significant increase in the regional volumes of cortical grey matter and myelinated white matter. The alterations in cerebral cortical grey matter and myelinated white matter volumes may provide insight into the established association of PHVD with deficits in cognitive and motor functions.