RT Journal Article
SR Electronic
T1 Supranuclear gaze palsy and opsoclonus after Diazinon poisoning
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 677
OP 679
DO 10.1136/jnnp.74.5.677
VO 74
IS 5
A1 T-W Liang
A1 L J Balcer
A1 D Solomon
A1 S R Messé
A1 S L Galetta
YR 2003
UL http://jnnp.bmj.com/content/74/5/677.abstract
AB A 52 year old man developed a supranuclear gaze palsy and opsoclonus after Diazinon poisoning. The diagnosis was confirmed by low plasma and red blood cell cholinesterase activity and urine mass spectroscopy. Saccadic control may be mediated in part by acetylcholine. Opsoclonus in the setting of organophosphate intoxication may occur as a result of cholinergic excess which overactivates the fastigial nuclei.