RT Journal Article
SR Electronic
T1 Effects of decompressive craniectomy on brain tissue oxygen in patients with intracranial hypertension
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 513
OP 515
DO 10.1136/jnnp.74.4.513
VO 74
IS 4
A1 M Jaeger
A1 M Soehle
A1 J Meixensberger
YR 2003
UL http://jnnp.bmj.com/content/74/4/513.abstract
AB This report examined the intraoperative course of partial pressure of brain tissue oxygen (PtiO2) and intracranial pressure (ICP) during surgical decompressive craniectomy for medically intractable intracranial hypertension due to diffuse brain swelling in three patients after severe subarachnoid haemorrhage and aneurysm coiling. The mean ICP decreased from 59 mm Hg to 10 mm Hg in a two step fashion, relating to bone flap removal and dural opening. Simultaneously, PtiO2 increased rapidly from 0.8 kPa (6 mm Hg) to 3.07 kPa (23 mm Hg). PtiO2 and ICP remained at non-critical ranges postoperatively. Despite these beneficial effects on ICP and PtiO2, the patients’ clinical status remained poor with two in a persistent vegetative state and one dead.