PT - JOURNAL ARTICLE AU - A Chieregato AU - F Calzolari AU - G Trasforini AU - L Targa AU - N Latronico TI - Normal jugular bulb oxygen saturation AID - 10.1136/jnnp.74.6.784 DP - 2003 Jun 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 784--786 VI - 74 IP - 6 4099 - http://jnnp.bmj.com/content/74/6/784.short 4100 - http://jnnp.bmj.com/content/74/6/784.full SO - J Neurol Neurosurg Psychiatry2003 Jun 01; 74 AB - Background: Normal values of the jugular bulb oxygen saturation were obtained in 1942 and in 1963. Correct catheter positioning was not confirmed radiologically. Objectives: To replicate the measurements during angiographic catheterisation of the jugular bulb. Methods: Oxygen saturation in the jugular bulb (SjO2), inferior petrosal sinus (SipsO2), and internal jugular vein was bilaterally measured in 12 patients with Cushing’s syndrome undergoing selective bilateral catheterisation of the inferior petrosal sinus. In addition, data from the two old series were reanalysed for comparison. Results: SjO2 values (44.7%) were significantly lower than in the two old series, particularly concerning the normal lower limit (54.6% and 55.0% respectively). Comparative analysis suggests that contamination with the extracerebral blood of the facial veins and inferior petrosal sinuses was responsible for falsely high SjO2 values in the two old series. Conclusions: The normal lower SjO2 limit is lower than previously recognised. This may have practical implications for treating severe head trauma patients.