TY - JOUR T1 - Experienced fatigue in facioscapulohumeral dystrophy, myotonic dystrophy, and HMSN-I JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 1406 LP - 1409 DO - 10.1136/jnnp.2004.050005 VL - 76 IS - 10 AU - J S Kalkman AU - M L Schillings AU - S P van der Werf AU - G W Padberg AU - M J Zwarts AU - B G M van Engelen AU - G Bleijenberg Y1 - 2005/10/01 UR - http://jnnp.bmj.com/content/76/10/1406.abstract N2 - Objective: To assess the prevalence of severe fatigue and its relation to functional impairment in daily life in patients with relatively common types of neuromuscular disorders. Methods: 598 patients with a neuromuscular disease were studied (139 with facioscapulohumeral dystrophy, 322 with adult onset myotonic dystrophy, and 137 with hereditary motor and sensory neuropathy type I). Fatigue severity was assessed with Checklist Individual Strength (CIS-fatigue). Functional impairments in daily life were measured with the short form 36 item health questionnaire (SF-36). Results: The three different neuromuscular patient groups were of similar age and sex. Severe experienced fatigue was reported by 61–74% of the patients. Severely fatigued patients had more problems with physical functioning, social functioning, mental health, bodily pain, and general health perception. There were some differences between the three disorders in the effects of fatigue. Conclusions: Severe fatigue is reported by the majority of patients with relatively common types of neuromuscular disorders. Because experienced fatigue severity is associated with the severity of various functional impairments in daily life, it is a clinically and socially relevant problem in this group of patients. ER -