PT  - JOURNAL ARTICLE
AU  - A S Cohen
AU  - P J Goadsby
TI  - Paroxysmal hemicrania responding to topiramate
AID  - 10.1136/jnnp.2006.096651
DP  - 2007 Jan 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 96--97
VI  - 78
IP  - 1
4099  - http://jnnp.bmj.com/content/78/1/96.short
4100  - http://jnnp.bmj.com/content/78/1/96.full
SO  - J Neurol Neurosurg Psychiatry2007 Jan 01; 78
AB  - Chronic paroxysmal hemicrania (CPH) is a rare primary headache syndrome, which is classified along with cluster headache and short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) as a trigeminal autonomic cephalalgia. CPH is exquisitely responsive to indomethacin so much so that the response is one of the current diagnostic criteria. The case of a patient with CPH, who had marked epigastric symptoms with indomethacin treatment and responded well to topiramate 150 mg daily, is reported. Cessation of topiramate caused return of episodes, and the response has persisted for 2 years. Topiramate may be a treatment option in CPH.