PT  - JOURNAL ARTICLE
AU  - Jürgen Andrich
AU  - Carsten Saft
AU  - Natalie Ostholt
AU  - Thomas Müller
TI  - Assessment of simple movements and progression of Huntington’s disease
AID  - 10.1136/jnnp.2006.105338
DP  - 2007 Apr 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 405--407
VI  - 78
IP  - 4
4099  - http://jnnp.bmj.com/content/78/4/405.short
4100  - http://jnnp.bmj.com/content/78/4/405.full
SO  - J Neurol Neurosurg Psychiatry2007 Apr 01; 78
AB  - Instrumental measurement of simple motion sequences reflects impairment in patients with Huntington’s disease (HD). The objectives were to study the progress of symptoms of HD and tapping results in 42 patients with HD, without symptomatic drug treatment over 3 years. Assessment moments were at baseline, and at years 1, 2 and 3. Unified Huntington’s Disease Rating Scale (UHDRS) total score and UHDRS arm score significantly increased. Motor test outcomes considerably worsened. Instrumental test results significantly correlated with both UHDRS scores at each assessment. Assessment of simple movement sequences is an additional simple method to follow impairment in patients with HD in addition to clinical rating.