@article {Asztely605, author = {Fredrik Asztely and Gerd Ekstedt and Bertil Rydenhag and Kristina Malmgren}, title = {Long term follow-up of the first 70 operated adults in the G{\"o}teborg Epilepsy Surgery Series with respect to seizures, psychosocial outcome and use of antiepileptic drugs}, volume = {78}, number = {6}, pages = {605--609}, year = {2007}, doi = {10.1136/jnnp.2006.098244}, publisher = {BMJ Publishing Group Ltd}, abstract = {Objective: To compare long term (10 years) seizure outcome, psychosocial outcome and use of antiepileptic drugs (AED) with the 2 year follow-up in adults after resective epilepsy surgery. Methods: All adults (nā€Š=ā€Š70) who underwent resective epilepsy surgery from 1987 to 1995 in the G{\"o}teborg Epilepsy Surgery Series were included. Fifty-four had undergone temporal lobe resections and 16 extratemporal resections (12 frontal). A cross-sectional follow-up in the form of a semistructured interview was performed in late 2003. Results: Mean follow-up was 12.4 years (range 8.6{\textendash}16.2). Of the 70 patients (51\% males), five (7\%) were dead (three as a result of non-epilepsy related causes). Of the 65 patients interviewed, 38 (58\%) were seizure-free at the long term follow-up: 65\% of the patients with temporal lobe resections and 36\% of the patients with extratemporal resections. Of the 35 patients who were seizure-free at the 2 year follow-up, 3 (9\%) had seizures at the long term follow-up. Of the 30 patients who had seizures at the 2 year follow-up, 6 (20\%) were seizure-free at the long term follow-up. Of all 65 patients, 45 (69\%) had the same seizure status as the 2 year follow-up. Sixteen (25\%) had an improved seizure status and 4 (6\%) had a worsened status. Of the seizure-free patients, 11 (29\%) had ceased taking AED, 28 (74\%) were working and 25 (66\%) had a driving license. Conclusions: Adult patients who are seizure-free 2 years after resective epilepsy surgery are most likely to still be seizure-free 10 years later. Most are working and have obtained a driving license.}, issn = {0022-3050}, URL = {https://jnnp.bmj.com/content/78/6/605}, eprint = {https://jnnp.bmj.com/content/78/6/605.full.pdf}, journal = {Journal of Neurology, Neurosurgery \& Psychiatry} }