PT  - JOURNAL ARTICLE
AU  - Asztely, Fredrik
AU  - Ekstedt, Gerd
AU  - Rydenhag, Bertil
AU  - Malmgren, Kristina
TI  - Long term follow-up of the first 70 operated adults in the Göteborg Epilepsy Surgery Series with respect to seizures, psychosocial outcome and use of antiepileptic drugs
AID  - 10.1136/jnnp.2006.098244
DP  - 2007 Jun 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 605--609
VI  - 78
IP  - 6
4099  - http://jnnp.bmj.com/content/78/6/605.short
4100  - http://jnnp.bmj.com/content/78/6/605.full
SO  - J Neurol Neurosurg Psychiatry2007 Jun 01; 78
AB  - Objective: To compare long term (10 years) seizure outcome, psychosocial outcome and use of antiepileptic drugs (AED) with the 2 year follow-up in adults after resective epilepsy surgery. Methods: All adults (n = 70) who underwent resective epilepsy surgery from 1987 to 1995 in the Göteborg Epilepsy Surgery Series were included. Fifty-four had undergone temporal lobe resections and 16 extratemporal resections (12 frontal). A cross-sectional follow-up in the form of a semistructured interview was performed in late 2003. Results: Mean follow-up was 12.4 years (range 8.6–16.2). Of the 70 patients (51% males), five (7%) were dead (three as a result of non-epilepsy related causes). Of the 65 patients interviewed, 38 (58%) were seizure-free at the long term follow-up: 65% of the patients with temporal lobe resections and 36% of the patients with extratemporal resections. Of the 35 patients who were seizure-free at the 2 year follow-up, 3 (9%) had seizures at the long term follow-up. Of the 30 patients who had seizures at the 2 year follow-up, 6 (20%) were seizure-free at the long term follow-up. Of all 65 patients, 45 (69%) had the same seizure status as the 2 year follow-up. Sixteen (25%) had an improved seizure status and 4 (6%) had a worsened status. Of the seizure-free patients, 11 (29%) had ceased taking AED, 28 (74%) were working and 25 (66%) had a driving license. Conclusions: Adult patients who are seizure-free 2 years after resective epilepsy surgery are most likely to still be seizure-free 10 years later. Most are working and have obtained a driving license.