RT Journal Article
SR Electronic
T1 Distal muscle involvement in granulomatous myositis can mimic inclusion body myositis
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 674
OP 677
DO 10.1136/jnnp.2009.190751
VO 82
IS 6
A1 Sandrine Larue
A1 Thierry Maisonobe
A1 Olivier Benveniste
A1 Catherine Chapelon-Abric
A1 Olivier Lidove
A1 Thomas Papo
A1 Bruno Eymard
A1 Odile Dubourg
YR 2011
UL http://jnnp.bmj.com/content/82/6/674.abstract
AB The authors report on four patients aged over 50 with chronic myopathy suggestive of sporadic inclusion body myositis. They present progressive and selective weakness of the quadriceps femoris muscles. Asymmetrical and selective atrophy of the forearm muscles were noted in all, with more severe involvement of the flexors than the extensors. Biopsy revealed granulomatous myositis. Histological features of sporadic inclusion body myositis were lacking. Evidence for systemic sarcoidosis was found in one patient. Corticosteroid treatment was associated with a partial but significant improvement in two patients. Granulomatous myositis may mimic inclusion body myositis and may be steroid-responsive.