RT Journal Article
SR Electronic
T1 Eye movements in amyotrophic lateral sclerosis and its mimics: a review with illustrative cases
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 110
OP 116
DO 10.1136/jnnp.2010.212407
VO 82
IS 1
A1 Donaghy, Colette
A1 Thurtell, Matthew J
A1 Pioro, Erik P
A1 Gibson, J Mark
A1 Leigh, R John
YR 2011
UL http://jnnp.bmj.com/content/82/1/110.abstract
AB Abnormal eye movements are increasingly recognised in patients with amyotrophic lateral sclerosis (ALS) and, when they occur, may provide insights into the pattern and pathogenesis of the disease process. In patients with disorders that mimic ALS, abnormal eye movements may point to the correct diagnosis. In both of these circumstances, systematic examination of eye movements and interpretation of the findings with reference to modern concepts of their neural substrate will aid diagnosis and suggest pathogenesis. Here, key points with illustrative case histories and eye movement records are highlighted.