RT Journal Article SR Electronic T1 Structural neuroanatomy of face processing in frontotemporal lobar degeneration JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP 1341 OP 1343 DO 10.1136/jnnp.2010.227983 VO 82 IS 12 A1 Omar, Rohani A1 Rohrer, Jonathan D A1 Hailstone, Julia C A1 Warren, Jason D YR 2011 UL http://jnnp.bmj.com/content/82/12/1341.abstract AB Impairments of face processing occur frequently in frontotemporal lobar degeneration (FTLD) but the neuroanatomical basis for these deficits has seldom been studied systematically. Here a prospective voxel based morphometry study is described addressing the neuroanatomy of two key dimensions of face processing—face identification and facial emotion recognition—in a single cohort of 32 patients with FTLD (19 with frontal variant and 13 with temporal variant FTLD). For the FTLD group as a whole, face identification was positively associated with grey matter in the right anterior fusiform gyrus while recognition of angry expressions was positively associated with grey matter in the bilateral insula cortex. FTLD provides a perspective on the neuroanatomy of face processing that is complementary to focal lesion and normal functional imaging work.