RT Journal Article SR Electronic T1 PA.01 The dorsal hippocampal commissure: when the functionality matters JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP e2 OP e2 DO 10.1136/jnnp-2011-300504.28 VO 82 IS 8 A1 Rosenzweig, I A1 Beniczky, S A1 Brunnhuber, F A1 Alarcon, G A1 Valentin, A YR 2011 UL http://jnnp.bmj.com/content/82/8/e2.21.abstract AB Aims The human hippocampal phylogeny is manifested by near or total disappearance of ventral hippocampal commissure. In contrast, the dorsal hippocampal commissure, although considered controversial and vehemently disputed by some groups, is believed to present a functional pathway in the human brain.Methods Gloor et al in 1993 proposed that, in humans, the spread though the dorsal hippocampal commissure is the only likely pathway of contralateral propagation for seizure discharges originating in mesial temporal structures with spread to the contralateral hippocampus.Results We report an unusual case of a patient with refractory temporal epilepsy (TLE) with several seizure types who underwent a comprehensive presurgical evaluation due to non-concordant results between various investigative modalities.Conclusions It is postulated here that repeated false lateralisation of seizure onset by extracranial EEG recordings in our patient might have been instigated by the distinct patterns of seizure spread utilising the dorsal hippocampal commissure.