TY - JOUR T1 - Increased premorbid physical activity and amyotrophic lateral sclerosis: born to run rather than run to death, or a seductive myth? JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 947 LP - 947 DO - 10.1136/jnnp-2013-304935 VL - 84 IS - 9 AU - Martin R Turner Y1 - 2013/09/01 UR - http://jnnp.bmj.com/content/84/9/947.abstract N2 - Osler noted, ‘It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has’. In amyotrophic lateral sclerosis (ALS), a previously functional motor system undergoes a catastrophic, typically rapid degeneration, with a median survival from symptom onset of 3 years.1 Understanding who is at high risk for what appears as a sporadic disorder for most is axiomatic to any long-term vision of primary prevention. Huisman et al2 now present a questionnaire-led, population-based, case–control study of 636 patients and 2166 controls in relation to premorbid physical activity.ALS abruptly ended the career of American … ER -