RT Journal Article
SR Electronic
T1 Depression in glioma: a primer for clinicians and researchers
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 230
OP 235
DO 10.1136/jnnp-2013-306497
VO 85
IS 2
A1 Alasdair G Rooney
A1 Paul D Brown
A1 Jacob C Reijneveld
A1 Robin Grant
YR 2014
UL http://jnnp.bmj.com/content/85/2/230.abstract
AB Depression is one of the leading causes of global disability, and a considerable hidden morbidity among patients with glioma. In this narrative review, we summarise what is currently known about depression in glioma, the main unanswered questions and the types of studies that should be prioritised in order to find out. We conclude by calling for a prospective Phase II study of antidepressants in depressed glioma patients, to test methodologies for a multicentre randomised controlled trial.